USCIS has stopped accepting the TB skin test

Since October 1, 2018, the tuberculin skin test (TST) is no longer accepted for US Citizenship and Immigration Services (USCIS) immigration exams (1). All US civil surgeons must now use a TB blood test (interferon-gamma release assay or IGRA) as the initial screening method when a test for cell-mediated immunity to TB is required. This requirement aligns with the most current CDC recommendations which state that IGRA testing is strongly preferred for those who are BCG-vaccinated.

Watch a free webinar on USCIS guidelines with Dr. Alawode Oladele

Watch our free on-demand webinar to learn more about the new IGRA requirement and additional details on the updated Technical Instructions. Learn how to interpret and manage IGRA results, and why this change is an important step in the CDC’s march toward TB elimination in the US. Dr. Oladele is the medical director of county-wide services for the DeKalb County Board of Health, Georgia, where he directs medical screening of 1,000–2,000 refugees annually.

Want to learn more about TB testing with QuantiFERON-TB Gold Plus?

Contact a QFT-Plus expert

Discover the benefits of the world’s leading IGRA, QuantiFERON-TB Gold Plus

  • Unlike the TST, QFT-Plus does not cross-react with the BCG vaccine – resulting in fewer false positive test results
  • TB testing with QFT-Plus is accurate, affordable and available in-office through your current lab service provider

Find out more about QFT-Plus at our Provider Resources Portal


1. Emily Jentes. Immigrant, Refugee, and Migrant Health Branch, US Centers for Disease Control and Prevention. "News/Update: Tuberculosis IGRA testing for US civil surgeons". 16th February, 2018.

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